Profile

Title

PhD

Full name

Joost P. Schanstra

Affiliation

Inserm U 858 – I2MR – Equipe 5
1 avenue Jean Poulhès
BP 84225
31432 Toulouse Cedex 4
France

Working group 2

Executive Committee

Management Committee

Keywords

Pediatric kidney disease, renal fibrosis, urinary proteomics, biomarkers, therapeutics

Publications

Pradère JP, Klein J, Grès S, Guigné C, Neau E, Valet P, Calise D, Chun J, Bascands JL, Saulnier-Blache JS, Schanstra JP. LPA1 Receptor Activation Promotes Renal Interstitial Fibrosis. J Am Soc Nephrol. 2007, 18, 3110-3118

Decramer S, Parant O, Beaufils S, Clauin S, Guillou C, Kessler S, Aziza J, Bandin F, Schanstra JP, Bellanné-Chantelot C. Anomalies of the TCF2 gene are the main cause of fetal bilateral hyperechogenic kidneys. J Am Soc Nephrol. 2007, 18, 923-933

Mischak H, Apweiler R, Bank RE, Conaway M, Coon J, Dominiczak A, Ehrich JHH, Fliser D, Girolami M, Goodsaid F, Hermjakob H, Hochstrasser D, Jankowski J, Julian BA, Kolch W, Massy ZA, Neusuess C, Novak J, Peter K, Rossing K, Schanstra JP, Semmes J, Theodorescu D, Thongboonkerd V, Weissinger E, Van Eyk JE, Yamamoto T. Clinical Proteomics: a need to define the field and to begin to set adequate standards. Proteomics Clin. Appl. 2007, 1, 148–156.

Decramer S, Wittke S, Mischak H, Zurbig P, Walden M, Bouissou F, BascandsJL, Schanstra JP. Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Nat Med. 2006, 12, 398-400

Schanstra JP, Neau E, Drogoz P, Arevalo Gomez MA, Lopez Novoa JM, Calise D, Pecher C, Bader M, Girolami JP and Bascands JL. In vivo Bradykinin B2-Receptor Activation Reduces Renal Fibrosis. J. Clin. Invest. 2002, 110, 371-379.

Brief Description

Our Inserm laboratory is located in Toulouse, France. Our main interest is in paediatric kidney disease focusing on renal fibrosis. We aim the identification of non-invasive biomarkers for the early detection of renal disease in the paediatric population and on the identification of new molecules/therapeutic-approaches able to slow down the progression of renal fibrosis.

Contact Information

Phone

+33 5 62 17 25 54

Fax

+33 5 61 32 37 48

Email

joost-peter.schanstra(at)inserm(dot)fr

Address

Inserm U 858 – I2MR – Equipe 5
1 avenue Jean Poulhès
BP 84225
31432 Toulouse Cedex 4
France

History

Member for

3 years 30 weeks