Profile

Title

Dr

Full name

Anja Verhulst

Affiliation

Laboratory of Pathophysiology
University of Antwerp
Universiteitsplein 1
2610 Antwerpen
Belgium

Working group 3

Management Committee

Keywords

Urine proteomics, nephrolithiasis, oxalate, primary human tubular cell culture, erythropoietin

Publications

Verhulst A., Asselman M, Persy VP, Schepers MS, Helbert MJ, Verkoelen CF and De Broe ME (2003) Crystal retention capacity of cells in the human nephron: involvement of CD44 and its ligands hyaluronic acid and osteopontin in the transition of a crystal binding into a nonadherent epithelium. J Am Soc Nephrol 14: 107-115.

Verhulst A, D’Haese PC and De Broe ME (2004) Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells. J Am Soc.Nephrol 15: 2249-2257.

Verhulst A, Asselman M, De Naeyer S, Vervaet BA, Mengel M, Gwinner W, D’Haese PC, Verkoelen CF, and De Broe ME (2005) Preconditioning of the distal tubular epithelium of the human kidney precedes nephrocalcinosis. Kidney Int 68: 1643-1647.

Persy VP, Verhulst A., Ysebaert DK, De Greef KE and De Broe ME (2003) Reduced postischemic macrophage infiltration and interstitial fibrosis in osteopontin knockout mice. Kidney Int. 63: 543-553.

Vervaet BA, Verhulst A, Dauwe S, Verberckmoes SC, De Broe ME and D’Haese PC (2008) An active renal crystal clearance mechanism in rat and man. Kidney Int 2008 (In press)

Brief Description

Since May 2003: post-doctoral researcher at the laboratory of Pathophysiology (former laboratory of Nephrology), University of Antwerp, Belgium.
Since October 2007: as a postdoctoral fellow of the Fund for Scientific Research Flanders (FWO).

Interests/expertise: nephrolithiasis/nephrocalcinosis, phosphate binding molecules (used for dialysis patients), erythropoietin as protection agent for the kidney, tubular transport of molecules, urinary proteomics

Tools available in the laboratory: rat models for different renal pathologies, primary human tubular kidney cell cultures, proteomics, lasure capture microdissection….

Contact Information

Phone

+32 3 820 25 79

Fax

+32 3 82 025 92

Email

anja.verhulst(at)ua(dot)ac(dot)be

History

Member for

2 years 9 weeks