Profile

Title

Assoc. Professor in Nephrology

Full name

Dimitrios S Goumenos

Affiliation

Department of Nephrology
University Hospital of Patras -Greece

Keywords

Glomerulonephritis, myofibroblasts, growth factors, apoptosis, renal scarring

Publications

Myofibroblasts, predictors of progression of mesangial IgA nephropathy?
Goumenos D.S., Brown C.B., Shortland J.R., El Nahas A.M.
Nephrology Dialysis Transplantation 1994; 9:1418-1425

Phenotypic modulation of renal cell during experimental and clinical renal scarring.
El Nahas A.M., Muchaneta-Kubara E.C., Zhang G., Adam A., Goumenos D.
Kidney International 1996; 49(Suppl.54):S23-S27

Transforming growth factor beta-1(TGF-β1) and myofibroblasts: A potential pathway towards renal scarring in human glomerular disease.
Goumenos D.S., Tsamantas A.C., Oldroyd S., Sotsiou F., Tsakas S., Petropoulou C., Bonikos D.S., El Nahas A.M., Vlachojannis J.G.
Nephron 2001; 87(3): 240-248.

Transforming growth factor -β1 in the kidney and urine of patients with glomerular disease and proteinuria.
Goumenos D.S., Tsakas S, El Nahas A.M., Alexandri S, Oldroyd S., Kalliakmani P., Vlachojannis J.G.
Nephrology Dialysis Transplantation 2002;12:2145-2152

Accurate measurement and clinical significance of urinary transforming growth factor-beta.
Tsakas S, Goumenos DS.
Am J Nephrol 2006; 26: 186-193

Brief Description

Renal Physician / Associate Professor in Nephrology in the Department of Nephrology of the University Hospital of Patras - Greece. The main topic of my clinical work is the management of patients with glomerulonephritis and renal transplantation. Treatment of patients with glomerulonephritis with immunosuppressive drugs and in particular the use of cyclosporin in patients with membranous nephropathy and nephrotic syndrome represent an important issue of my clinical research. Our research activity is also focused in the study of the mechanisms involved in the pathogenesis of glomerular disease and in the progression of renal scarring. The latter includes the detection of growth factors (TGF-beta), myofibroblasts and markers of the apoptotic process in the renal tissue and urine of patients with glomerulonephritis. We have an ongoing collaboration with Prof AM El Nahas (Sheffield Kidney Institute, University of Sheffield, UK) over the last 10 and more years in the study of factors involved in the pathogenesis of renal scarring. I strongly believe that proteomic analysis in kidney tissue and urine of patients with glomerular diseases will give additional information in the field of renal scarring and our activity is now moving towards this direction.

Contact Information

Phone

00302610999366

Fax

00302610994424

Email

dgoumenos(at)med(dot)upartas(dot)gr

History

Member for

3 years 29 weeks