Profile

Title

co-Director Proteomics Research Unit

Full name

Antonia Vlahou

Affiliation

Division of Biotechnology- Proteomics Research Unit
Biomedical Research Foundation, Academy of Athens,
Soranou Efessiou 4, 11527,
Athens, Greece

Working group 3

Executive Committee

Management Committee

Keywords

urine, bladder cancer, two-dimensional electrophoresis, mass spectrometry, secretome

Publications

Manousos Makridakis, Sarantis Gagos, Andreas Petrolekas, Maria G Roubelakis, Vasiliki Bitsika, Konstantinos Stravodimos, Kitty Pavlakis, Nicholas P Anagnou, Jonathan Coleman and Antonia Vlahou
Chromosomal and proteome analysis of a new T24-based cell line model for
aggressive bladder cancer (Proteomics, in press)

Karamessinis PM, Malamitsi-Puchner A, Boutsikou T, Makridakis M, Vougas K, Fountoulakis M, Vlahou A, Chrousos G. Marked defects in the expression and glycosylation of alpha2-HS glycoprotein/fetuin-A in plasma from neonates with intrauterine growth restriction: proteomics screening and potential clinical implications. Mol Cell Proteomics. (2008) 7(3):591-9.

Zerefos PG, Vlahou A. Urine sample preparation and protein profiling by two-dimensional electrophoresis and matrix-assisted laser desorption ionization time of flight mass spectroscopy. Methods Mol Biol. (2007);428:141-58

Panagiotis Zerefos, Julien Prados, Sophia Kossida, Alexandros Kalousis and Antonia Vlahou. Sample Preparation and Bioinformatics in MALDI Profiling of Urinary Proteins. J Chromat B (2007) 853(1-2):20-30

P. Zerefos, K. Vougas, P. Dimitraki, S. Kossida, A. Petrolekas, K. Stavrodimos, A. Giannopoulos, M. Fountoulakis and A. Vlahou. Characterization of the human urine proteome by preparative electrophoresis in combination to two-dimensional electrophoresis. Proteomics, (2006), 6(15):4346-55

Brief Description

Vlahou received her BS from the School of Biology, University of Athens, Greece and her Ph.D from the Department of Cell Biology, Baylor College of Medicine, Houston, Texas. Vlahou pursued post-doctoral studies at the Eastern VA Medical School, USA, where she was appointed as a research assistant professor from 2001 to 2003 when she moved to the Biomedical Research Foundation, Academy of Athens (BRFAA), Greece. Vlahou is currently the co-Director of the Proteomics Research Unit at BRFAA. Vlahou is one of the founding members and currently the President of the Hellenic Proteomics Society. For her studies, she currently receives funding from the Greek Department of Health and the FP7 program DECanBio.
The research interests of Vlahou’s group include: a) Identification of urinary biomarkers for bladder cancer and other urogenital diseases by the use of comprehensive two-dimensional electrophoresis and MS- based approaches; b) Identification of proteins involved in the acquisition of cell aggressive phenotype. There is special interest in the characterization of secreted proteins and for their study cell line and animal models for aggressive bladder cancer are employed.

Contact Information

Phone

+30 210 6597 506

Fax

+30 210 6597 545

Email

vlahoua(at)bioacademy(dot)gr

History

Member for

3 years 32 weeks